Guy Bresler is the Bonnie and Marty (1964) Tenenbaum Career Development Professor. His research investigates the relationship between combinatorial structure and computational tractability of high-dimensional inference in graphical models and other statistical models. Some of his recent work studies how best to learn a graphical model from data, and how data and computation requirements can be reduced if the model is to be subsequently used for a specific inference task. Guy is also interested in applications of these methods, especially to recommendation systems and computational biology.